Expresión de búsqueda: AUTOPHAGY-RELATED PROTEIN 7 
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Descriptor Inglés:   Autophagy-Related Protein 7 
Descriptor Español:   Proteína 7 Relacionada con la Autofagia 
Descriptor Portugués:   Proteína 7 Relacionada à Autofagia 
Sinónimos Inglés:   ATG12-Activating Enzyme E1 ATG7
ATG7 Protein
Ubiquitin-Activating Enzyme E1-like Protein
Ubiquitin-Like Modifier-Activating Enzyme ATG7
ATG12 Activating Enzyme E1 ATG7
Autophagy Related Protein 7
Ubiquitin Activating Enzyme E1 like Protein
Ubiquitin Like Modifier Activating Enzyme ATG7  
Categoría:   D12.776.094.399
Definición Inglés:   An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition. 
Nota Histórica Inglés:   2017 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   56559 
Identificador Único:   D000071193 

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